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Med cannabis hits high notes for pain mgmt, rare diseases

Med cannabis hits high notes for pain mgmt, rare diseases Three year-old Sis CBD OIL TO BE BILLION-A CANNABIS PRIMER DOLLAR INDUSTRY' lathy lyer@timesgroup.com mbal : changed) was nine months old when she was di nosed with Van der Knapp ndrome, a rare disorder in the brain's white mater progressively starts vanshing She couldn't hold her in position, turn or crawl ke other toddlers, and neu ologists whom her techie par ents consulted said there was no medicine or treatment they could offer their daughter family Cannabis Or Marijuana? > Cannabis and marijuana are used interchangeably, but they don't mean the same thing > Cannabis is the name for all products derived from the plant Cannabis sativa At that time, the doctor gave an unconventional advice: Try medical cannahis oil for Sia "We followed advice, and Sia has in the two years developed a range of movements that our neurologist was surprised at," said her 32-year-old mother > The plant has about 540 chemical substances ➤ Marijuana is one of these products and contains tetrahydrocannabinol that alters mental state & causes a "high" Medical cannabis Certain chemical substances from cannabis plant-known as cannabinoids-are used for medical purposes For Shruti Shridhar, the doctor who gave Maya the advice, Sia was the first patient for whom she had prescribed medical cannabis. "When Sia's condition was diagnosed in October 2020, I started re searching Van der Knapp syndrome to understand the phystology I found a research arti They have been approved for use in various countries ➤The US Food and Drug Administration has approved several drugs that contain individual cannabinoids USED FOR IN CONDITIONS Pain | Helping to decrease opioid use | Anxiety | Epilepsy HIV/AIDS symptoms | Inflammatory bowel disease Irritable bowel syndrome Movement disorders due to Tourette Syndrome | Multiple Sclerosis Nausea and vomiting related to cancer chemotherapy | Post-traumatic stress disorder (PTSD) the uid For example Epidiolex was approved for the treatment of selzures associated with Lennox-Gastaut Syndrome or Dravet Syndrome, two rare and severe forms of epilepsy cle that mentioned CBD oil could cause neuroprotection and neurogenesis in forming of new neurons," she told TOL ➤ Dronabinol and nabilone are used in nausea, vomiting caused by cancer chemotherapy THE HEALTH RISKS > Use linked to an increased risk of motor vehicle crashes Medical cannabis can be in form of pill, liq, oil, powder, dried leaves > Dronabinol is also used to treat loss of appetite, weight loss in people with HIV/AIDS Smoking cannabis during pregnancy linked to lower birth weight practitioners, the problem begins right with the nomenclature: People think cannabis is the same as marijuana, which is associated with "highs" and Some develop cannabis use disorder; symptoms include craving, withdrawal, lack of control, negative effects on personal, professional responsibilities Adolescents using cannabis 4 to 7 times more likely than adults to develop cannabis use disorder Use, especially frequent use, linked to a higher risk of schizophrenia or other psychoses in people who are predisposed to these ➤ Marijuana may cause orthostatic hypotension (head rush or dizziness on standing up), raising danger from fainting Cannabis in India Sleep problems ➤In use as bhang for centuries Bhang is derived from leaves of cannabis plant Ayurvedic preparations use bhang-like preparations The research paper wasn't new, but there is such low ac ceptance or understanding about medical cannabis that no doctor seemed to have heard of its ability to help children like Sia. For a country where bhang, a product made from cannabis leaves, has been in use for centuries, knowledge about cannabis's medical uses is extremely low. To change this, Pune-based Shridhar and other members of Academy of Cannabinoids Indla last week spoke about the 'Why how and what of medical cannabis' to an audience comprising doctors and interested citizens in central Mumbai. >Needs prescription, usually not prescribed by al-lopathic doctors Source: US National Center For Complementary NDPS Act bans charas in resin form, ganja flowerIng or fruiting tops of cannabis plant Health & Cannabis Clinic India, Pune nogenic effects. Cannabis is the name of the entire plant whose various parts contain about 540 chemicals. Cannabidiol oil, or CBD oil, is an active ingredient in cannabis and most commonly used as medical cannabis, said doctors. tients, most with chronic pain related to either cancer or neurological diseases such as multiple sclerosis. Her mentor, Palakkad-based allopath Sayed Tahir Hassan has treated over 5,000 patients since he started with medical cannabis care in 2017. vis medical cannabis in the past five years, according to Hassan, is that cancer patients come to him right at the start. "Previously, I would only get patients in the last stages, but now I get patients in stage two," he said. "I have trained 45 doctors across the country since then and I now mainly help cancer patients with pain manage ment," he said. In the two years that she has started her cannabis clinic, Shridhar has over 200 pa The biggest change vis-à For cannabis practitioners, the problem begins right R 20 www. Two years back, United Nations reclassified cannabis from Schedule IV where it was listed alongside heroin to encourage scientific research into the plant's medicinal prop erties. Maya

Mumbai Three year-old Sia (name changed) was nine months old when she was dianosed with Van der Knapp syndrome, a rare disorder in which the brain's white mater progressively starts vanshing She couldn't hold her in position, turn or crawl like other toddlers, and neurologists whom her techie parents consulted said there was no medicine or treatment they could offer their daughter.

At that time, the family doctor gave an unconventional advice: Try medical cannahis oil for Sia "We followed advice, and Sia has in the two years developed a range of movements that our neurologist was surprised at," said her 32-year-old mother maya.

For Shruti Shridhar, the doctor who gave Maya the advice, Sia was the first patient for whom she had prescribed medical cannabis. "When Sia's condition was diagnosed in October 2020, I started researching Van der Knapp syndrome to understand the phystology I found a research article that mentioned CBD oil could cause neuroprotection and neurogenesis in forming of new neurons," she told TOI.

The research paper wasn't new, but there is such low ac ceptance or understanding about medical cannabis that no doctor seemed to have heard of its ability to help children like Sia. For a country where bhang, a product made from cannabis leaves, has been in use for centuries, knowledge about cannabis's medical uses is extremely low. To change this, Pune-based Shridhar and other members of Academy of Cannabinoids Indla last week spoke about the 'Why how and what of medical cannabis' to an audience comprising doctors and interested citizens in central Mumbai.

For cannabis practitioners,the problem begins right with the nomenclature: People think cannabis is the same as marijuana, which is associated with "highs" and hallucinogenic effects. Cannabis is the name of the entire plant whose various parts contain about 540 chemicals. Cannabidiol oil, or CBD oil, is an active ingredient in cannabis and most commonly used as medical cannabis, said doctors.

CBD OIL TO BE BILLION-DOLLAR INDUSTRY'

A CANNABIS PRIMER

Cannabis Or Marijuana?

Cannabis and marijuana are used interchangeably, but they don't mean the same thing

Cannabis is the name for all products derived from the plant Cannabis sativa

The plant has about 540 chemical substances

Marijuana is one of these products and contains tetrahydrocannabinol that alters mental state & causes a "high"

Medical cannabis

Certain chemical substances from cannabis plant-known as cannabinoids-are used for medical purposes

They have been approved for use in various countries

The US Food and Drug Administration has approved several drugs that contain individual cannabinoids

For example Epidiolex was approved for the treatment of selzures associated with Lennox-Gastaut Syndrome or Dravet Syndrome, two rare and severe forms of epilepsy

Dronabinol and nabilone are used in nausea, vomiting caused by cancer chemotherapy

Dronabinol is also used to treat loss of appetite, weight loss in people with HIV/AIDS

USED FOR IN CONDITIONS

Pain | Helping to decrease opioid use | Anxiety | Epilepsy HIV/AIDS symptoms | Inflammatory bowel disease Irritable bowel syndrome Movement disorders due to Tourette Syndrome | Multiple Sclerosis Nausea and vomiting related to cancer chemotherapy | Post-traumatic stress disorder (PTSD) sleep problems

THE HEALTH RISKS

Use linked to an increased risk of motor vehicle crashes

Smoking cannabis during pregnancy linked to lower birth weight

Some develop cannabis use disorder; symptoms include craving, withdrawal, lack of control, negative effects on personal, professional responsibilities

Adolescents using cannabis 4 to 7 times more likely than adults to develop cannabis use disorder

Use, especially frequent use, linked to a higher risk of schizophrenia or other psychoses in people who are predisposed to these

Marijuana may cause orthostatic hypotension (head rush or dizziness on standing up), raising danger from fainting

Cannabis in India

In use as bhang for centuries Bhang is derived from leaves of cannabis plant Ayurvedic preparations use bhang-like preparations

Needs prescription, usually not prescribed by allopathic doctors

NDPS Act bans charas in resin form, ganja flowerIng or fruiting tops of cannabis plant

Medical cannabis can be in form of pill, liq, oil, powder, dried leaves

In the two years that she has started her cannabis clinic, Shridhar has over 200 patients, most with chronic pain related to either cancer or neurological diseases such as multiple sclerosis. Her mentor, Palakkad-based allopath Sayed Tahir Hassan has treated over 5,000 patients since he started with medical cannabis care in 2017.

"I have trained 45 doctors across the country since then and I now mainly help cancer patients with pain manage ment," he said.

The biggest change vis-à-vis medical cannabis in the past five years, according to Hassan, is that cancer patients come to him right at the start. "Previously, I would only get patients in the last stages, but now I get patients in stage two," he said.

Two years back, United Nations reclassified cannabis from Schedule IV where it was listed alongside heroin to encourage scientific research into the plant's medicinal prop erties.